INORGANIC PHOSPHIDES
Toxicology The most common cause of severe toxicity with inorganic phosphides in humans are due to ingestion of aluminium phosphide (ALP) and Zinc phosphide. Inhalational and absorption through eyes, skin …
Read MoreAcute Toxic Agents
These are toxicants that cause severe to moderately severe adverse effects on single exposure. The effects are oftentimes seen within hrs or few days after exposure.
Fluoroquinolone Toxicity
Toxicology The most severe adverse effects of fluoroquinolones (FQs) include toxicities of the gastrointestinal tract, central nervous system, cardiovascular system, and musculoskeletal system. The commonest adverse events are gastrointestinal tract …
Read MoreCLOFENTEZINE
Toxicology • Clofentezine is an acaricide with low mammalian toxicity (Oral LD50 > 5000 mg/kg)(IPCS, 2005;AAKO, 2006). • Its mode of toxicity is not understood(IPCS, 2005). • At high doses …
Read MoreTRIAZOLINTHIONE FUNGICIDES
Toxicology • The mammalian pharmacokinetic studies showed that prothioconazole was rapidly and extensively (> 90%) absorbed from the gastrointestinal tract, the tmax being 0.1–0.7hrs(FAO;D.B. McGregor DB and Soleck R, 2008;National …
Read MoreCARBAMATES
Toxicology • Carbamates include methomyl,pirimicarb carbofuran, aldicarb They are clinically similar to but chemically different from organophosphates. Carbamate insecticides, like the OP insecticides, inhibit AChE and elicit cholinergic hyperstimulation. However, …
Read MoreTRIAZINONE
Toxicology • Just like triazine, triazinone inhibit aliphatic amino acid synthesis in plants, a non-existent pathway in mammalian species hence a generally low degree of mammalian toxicity of the technical …
Read MoreORGANOTIN MITICIDES
Toxicology • The trimethyl and triethyltin compounds are well absorbed from the gastrointestinal tract and are the most toxic in this group (Kimbrough R D, 1976). • Some butyltin compounds …
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