Fenazaquin

• Fenazaquin is moderatelyacutely toxic (LD50 134/138 mg/kg ) (EPA, 2007)
• Most of ingested fenazaquin is excreted primarily in the excreta and a little in the urine, mostly as metabolites(EPA, 2007;National Center for Biotechnology Information, 2015)
• The mode of toxicity is disruption of mitochondrial function by inhibiting mitochondrial electron transport at the Complex I site (NADH-ubiquinone reductase) and cause oxidative damage in mites and some insects and possibly in human toxicity(EPA, 2007;National Center for Biotechnology Information, 2015)
• The oxidative damage could be reduced by NDI1 or by the antioxidants alpha-tocopherol . . .

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