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Basic first aid for the eye and skin

Eye Immediately flush eyes with plenty of water for at least 15min. Get medical help. Skin Wash skin with soap...
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Basic first aid for the eye and skin

Specific Management

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SALICYLANILIDE ANTHELMINTIC

The molecular mode of action of halogenated salicylanilide, including closantel, niclosamide,oxyclozanide, rafoxanide and resorantel is not completely elucidated. Salicylanilides, also referred to as benzamides or salicylamides, are weak,acidic phenolic compounds (Swan …

DICHLOROACETAMIDE safeners

PYRIMIDINYL CARBOXY HERBICIDE

BENZOYLPYRAZOLE

BENZOIC ACID

Poison Management

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Anticholinergic poisoning

Associated with impairment of normal cooling mechanisms such as sweating Treatment: Supportive care including active cooling and benzodiazepines NOTE: It is difficult to differentiate the toxic hyperthermic syndromes including hyperthermia …

Malignant Hyperthermia

Neuroleptic malignant syndrome (NMS)

Acute Toxic Agents

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Soil fumigant

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Termiticide

Insecticide/Miticide

Tribenuron-methyl

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Tifensulfuron

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Why Is Magadi Soda Added to Snuff and Chewing Tobacco?

The practice is rooted in basic nicotine toxicokinetics. Nicotine is a weak base (pKa ≈ 8.0) that exists in equilibrium ...
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Acute Vitamin A Toxicity

Vitamin A is a fat-soluble nutrient essential for vision, immune function, cellular differentiation, and maintenance of epithelial tissues. It comes ...
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Sulfa Allergy Explained: Why Structure Matters More Than Sulfur

Allergic reactions to sulfonamide antibiotics, such as sulfamethoxazole in cotrimoxazole, are not simply due to the presence of sulfur. Instead, ...
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Seizure Management in GABA Agonist Intoxication: Why Barbiturates Outperform Benzodiazepines

Several pesticide classes act on GABA receptors, but only a subset function as true agonists. Legacy cyclodienes such as dieldrin ...
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DNA Damage, Inflammation, and Disease: The Cost of Reusing Oil

Repeated heating, cooling, and reheating of cooking oil triggers thermal oxidation, hydrolysis, and polymerization. These reactions break down triglycerides and ...
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Laboratory Markers in the Diagnosis of Intrahepatic vs Extrahepatic Cholestasis

Clinical Pearls Pattern recognition is key: Intrahepatic cholestasis → hepatocellular enzymes (AST/ALT) rise alongside cholestatic markers. Extrahepatic cholestasis → disproportionate ...
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Factors Influencing the Routes of Poison Elimination

The route of elimination of xenobiotics is determined by their physicochemical properties (lipophilicity, polarity, molecular size), extent of metabolism, and ...
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Risperidone Toxicity

Toxicology Risperidone is a benzisoxazole compound that was approved for use in the United States in 1994 for patients with ...
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