Basic first aid for the eye and skin
Eye Immediately flush eyes with plenty of water for at least 15min. Get medical help. Skin Wash skin with soap...
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Poison Management
View AllAnticholinergic poisoning
Associated with impairment of normal cooling mechanisms such as sweating Treatment: Supportive care including active cooling and benzodiazepines NOTE: It is difficult to differentiate the toxic hyperthermic syndromes including hyperthermia …
Acute Toxic Agents
View AllWhy Is Magadi Soda Added to Snuff and Chewing Tobacco?
The practice is rooted in basic nicotine toxicokinetics. Nicotine is a weak base (pKa ≈ 8.0) that exists in equilibrium ...
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Acute Vitamin A Toxicity
Vitamin A is a fat-soluble nutrient essential for vision, immune function, cellular differentiation, and maintenance of epithelial tissues. It comes ...
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Sulfa Allergy Explained: Why Structure Matters More Than Sulfur
Allergic reactions to sulfonamide antibiotics, such as sulfamethoxazole in cotrimoxazole, are not simply due to the presence of sulfur. Instead, ...
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Seizure Management in GABA Agonist Intoxication: Why Barbiturates Outperform Benzodiazepines
Several pesticide classes act on GABA receptors, but only a subset function as true agonists. Legacy cyclodienes such as dieldrin ...
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DNA Damage, Inflammation, and Disease: The Cost of Reusing Oil
Repeated heating, cooling, and reheating of cooking oil triggers thermal oxidation, hydrolysis, and polymerization. These reactions break down triglycerides and ...
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Laboratory Markers in the Diagnosis of Intrahepatic vs Extrahepatic Cholestasis
Clinical Pearls Pattern recognition is key: Intrahepatic cholestasis → hepatocellular enzymes (AST/ALT) rise alongside cholestatic markers. Extrahepatic cholestasis → disproportionate ...
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Factors Influencing the Routes of Poison Elimination
The route of elimination of xenobiotics is determined by their physicochemical properties (lipophilicity, polarity, molecular size), extent of metabolism, and ...
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Risperidone Toxicity
Toxicology Risperidone is a benzisoxazole compound that was approved for use in the United States in 1994 for patients with ...
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