Toxicology
Pyrimidinylthiobenzoates
This family includes bispyribac-sodium, pyrithiobac-sodium,pyriminobac-methyl
Adjuvants such as non-ionic surfactants and petroleum based oils may be added to improve herbicidal efficacy
The mode of action has been considered as inhibition of acetolactate synthase (ALS-ase) in the biosynthetic pathway of three branched-chain amino acids .
Clinical Management
Because this class is of low toxicity the possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it . . .
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