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Acute Toxic Agents

These are toxicants that cause severe to moderately severe adverse effects on single exposure. The effects are oftentimes seen within hrs or few days after exposure.

Acute Toxic Agents / Chemical Class / Specific Management

STROBILURINS

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Inhibits cytochrome complex and thus antagonizes electron transfer that finally causes inhibition of mitochondrial respiration( Roberts and Reigart, 2013) • They produce relatively low toxicity; most strobilurins report …

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Acute Toxic Agents / Chemical Class / Specific Management

IRON SALTS

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology Acute iron toxicity is usually seen in children less than 5 years of age  who present with accidental ingestion of iron supplements. The main causes of iron poisoning in adults …

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Acute Toxic Agents / Chemical Class / Specific Management

FORMAMIDES

October 31, 2017November 15, 2024 - by Poison Sense

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Acute Toxic Agents / Chemical Class / Specific Management

IMIDAZOLINONE HERBICIDES

October 31, 2017December 19, 2025 - by Poison Sense

Toxicology Imazaquin, imazamethabenz-methyl, imazapyr, Imazapic, imazethapyr, and imazamox belong to a class of synthetic compounds called imidazolinone herbicides with a carboxylic acid group attached to the backbone Imidazolinones show low toxicity …

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Acute Toxic Agents / Chemical Class / Specific Management

PHENYLPYRAZOLE

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Inhibits the passage of chloride ions through GABA-gated chloride channels, resulting in neuronal hyper-excitability (Roberts and Reigart, 2013). • It’s rapidly absorbed from the GIT and the rapidly …

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Acute Toxic Agents / Chemical Class / Specific Management

ARYLOXYPHENOXY COMPOUNDS

October 31, 2017October 28, 2025 - by Poison Sense

Toxicology Aryloxyphenoxypropionates, a subfamily of the aromatic carboxylic acid family (including 2,4-D, dicamba)(Herbicides, 1997). Absorption of aryloxyphenoxypropionates (ArOPPs) are very rapid in animals by oral route Animals rapidly de-esterify ester …

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Acute Toxic Agents / Chemical Class / Specific Management

ORGANOPHOSPHATES

October 31, 2017October 1, 2026 - by Poison Sense

Toxicology  Based on the substituent attached to the phosphorus via a double bond, organophosphorus compounds (OPs) can be divided into phosphates (P=O) or phosphorothioates (P=S) (Costa GL 2008) Most OPs …

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Acute Toxic Agents / Chemical Class / Specific Management

TRIAZOLINONE

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • The technical grade Amicarbazone (active ingredient only) exhibits low acute toxici profile of LD50 (Males) = 1300 mg/kg and LD 50 (Females) = 1015 mg/kg (California Environmental Protection …

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Acute Toxic Agents / Chemical Class / Specific Management

ALKYLPHENOLS

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Alkylphenol ethoxylates are non-ionic surfactants (Warhurst AM, 1995) • Alkylphenols includes nonylphenol (most predominant) and octylphenol (Warhurst AM, 1995; Kayama et al., 2003) • Alkylphenol ethoxylates are biodegraded …

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Acute Toxic Agents / Chemical Class / Specific Management

HYPOCHLORITE

October 31, 2017January 29, 2026 - by Poison Sense

Toxicology Calcium hypochlorite is generally available as a white powder, pellets, or flat plates. It decomposes readily in water or when heated, releasing oxygen and chlorine (ATSDR, 2014) Sodium hypochlorite …

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Popular Posts

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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