OXYACETAMIDE
Toxicology • Acute toxicity studies have not been performed on this formulationt as formulated. • The median acute toxic level in rats varies according to sex from 371 mg/kg-1365 mg/kg …
Read MoreChemical Class
This is the category based on a number of factors including chemical structure or the mechanism of action or toxicity.
INFORMATION that is provided includes the toxicology of the compounds in this class, as well as the clinical manifestations and management of acute toxicity.
SPINOSYN INSECTICIDES
Toxicology • Most ingested spinosym are rapidly absorbed (peak blood conc in 1-6hrs) and eliminated primarily by faecal route. In one study, faecal excretion accounted for 85–88% of the administered …
Read MoreTOXIC MUSHROOM
Toxicology There are 14 distinctive types of mushroom poisoning found worldwide (NAMA) Identification of specific species is difficult, so treatment usually is guided by symptoms (O’Malley and O’Malley, 2015). Even …
Read MoreBENZIMIDAZOLES
Toxicology • Included in this group are benomyl, thiabendazole, thiophanate,thiophanate-methyl, carbedazim, Imazalil and fuberidazol (Rouabhi R, 2010) • Benomyl and carbendazim show low acute toxicity (Oruc HH, 2010). Benomyl is …
Read MorePYRROLE INSECTICIDES
Toxicology • Chlorfenapyr is a pro-compound that is activated insitu by oxidative removal of the N-ethoxymethyl group of chlorfenapyr by mixed-function oxidases to form the compound CL 303268 which may …
Read MoreBRIDGED DIPHENYL
Toxicology Bridged diphenyl acaricides are more or less structurally related to DDT(an organochlorine) Liver and kidney in rats and liver in mice were the major target organs of DDS toxicity …
Read MoreCARBON MONOXIDE
Toxicology The sources of CO may external or internal. Internal exposures to carbon monoxide occur as a result of production of carbon monoxide from endogenous compounds (e.g., heme degradation, auto-oxidation …
Read MorePHENOTHIAZINES
Toxicology • Phenothiazines includes the following medicines: •Chlorpromazine •Fluphenazine •Haloperidol •Promethazin Their therapeutic action is thought to be chiefly by antagonism of central dopaminergic (D2 receptor) neurotransmission, in addition to …
Read MorePYRIDINE HERBICIDES
Toxicology • They act as growth hormone auxin causing uncontrolled an d disorganized growth in susceptible plant species(CATs) . • It is common in two forms: triethylamine salt and butoxyethyl …
Read MoreCOMPLEX I INHIBITORS
Toxicology • Structurally diverse synthetic insecticides and acaricides had been shown to inhibit the proton-translocating NADH:ubiquinone oxidoreductase (complex I) activity (Lummen P, 1998). • The acute toxicity profile of pyridaben …
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