Toxicology
- includes Pyrifluquinazon and Fenazaquin
- Fenazaquin is moderately acutely toxic (LD50 134-138 mg/kg ) (EPA, 2007)
- Most of ingested fenazaquin is excreted primarily in the feces and a little in the urine, mostly as metabolites (EPA, 2007;National Center for Biotechnology Information, 2015)
- The mode of toxicity is by disruption of mitochondrial function by inhibiting mitochondrial electron transport chain through inhibition of the proton translocating NADH:ubiquinone oxidoreductase (complex I) activity. This inhibition results in oxidative damage to mites and possibly humans (EPA, 2007;National Center for Biotechnology Information, 2015) Please Subscribe to continue reading
