PYRAZOLE INSECTICIDES

Toxicology
• Moderate oral toxicity was observed in rats and mice, with LD50 values ranging from 245 to 520 mg/kg bw(IPCS INCHEM) • Fenpyroximate and tebufenpyrad are well absorbed in laboratory animals after oral administration(National Center for Biotechnology Information, 2015) .
• Are widely metabolised with little of the parent compound appearing in the urine or feces(National Center for Biotechnology Information, 2015) .
• Absorbed fenpyroximate is excreted predominantly via the biliary route, with lesser amounts in urine(National Center for Biotechnology Information, 2015).
• Fenpyroximatet is reported to inhibit the mitochondrial complex I from rat liver and from spider mites(National Center . . .

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