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Chemical Class

This is the category based on a number of factors including chemical structure or the mechanism of action or toxicity.
INFORMATION that is provided includes the toxicology of the compounds in this class, as well as the clinical manifestations and management of acute toxicity.

Acute Toxic Agents / Chemical Class / Specific Management

PHENYLAMIDES and DITHIOCARBAMATES

November 5, 2017June 9, 2023 - by Poison Sense

Clinical Management • Manage as for the individual active components i.e. phenylamides and dithiocarbamate . . . Please Subscribe to continue reading  

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Acute Toxic Agents / Chemical Class / Specific Management

ORGANOPHOSPHATES and NEONICOTINOID

November 5, 2017June 9, 2023 - by Poison Sense

Clinical Management Manage as for the individual organophosphate poisoning and neonicotinoid poisoning . . . Please Subscribe to continue reading  

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Acute Toxic Agents / Chemical Class / Specific Management

TRICYCLIC ANTIDEPRESSANTS

November 5, 2017June 10, 2023 - by Poison Sense

 Toxicology Please Subscribe to continue reading  

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Acute Toxic Agents / Chemical Class / Specific Management

PHENYLAMIDES

November 5, 2017June 10, 2023 - by Poison Sense

Toxicology • The cardiotoxic effects is mediated by alpha 1-adrenoreceptor activity since it is blocked by alpha 1-adrenoreceptor antagonist sauch as phentolamine (a nonselective alpha-adrenoreceptor antagonist) and prazosin (an alpha …

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Acute Toxic Agents / Chemical Class / Specific Management

THIOCARBAMATES

November 5, 2017June 10, 2023 - by Poison Sense

Toxicology • As a chemical family, the thiocarbamates are a group of pesticides with a wide range of uses. Some are used as fungicides, while others have herbicidal activity (Fishel …

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Acute Toxic Agents / Chemical Class / Specific Management

BARBITURATES

November 5, 2017June 8, 2023 - by Poison Sense

Toxicology At low doses, barbiturates bind to GABA-sensitive ion channels in CNS, leading increased influx of chloride ions into cell membranes where they produce hyperpolarization of post synaptic neurone (Lafferty …

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Acute Toxic Agents / Chemical Class / Specific Management

DINITROANILINE

November 5, 2017December 7, 2025 - by Poison Sense

Toxicology • Exposure route is by inhalation of its aerosol, through the skin and by ingestion (National Center for Biotechnology Information, 2015) • Oral exposure to rats showed low toxicity …

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Acute Toxic Agents / Chemical Class / Specific Management

ORGANOCHLORINE

November 5, 2017June 8, 2023 - by Poison Sense

Toxicology • The organochlorine (OCs) insecticides belong to three distinct chemical classes including the dichlorodiphenylethane, chlorinated cyclodiene and chlorinated benzene cyclohexane-related structures (Ecobichon DJ, 2008). • The LD50s of OCs …

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Acute Toxic Agents / Chemical Class / Specific Management

TRIFLUOROMETHYL AMINOHYDRAZONE

November 5, 2017June 8, 2023 - by Poison Sense

 Toxicology • Hydramethylnon acts by disrupting energy production in the cells. It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. …

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Acute Toxic Agents / Chemical Class / Specific Management

NICOTINE

October 31, 2017October 27, 2026 - by Poison Sense

Toxicology Acute nicotine poisoning may occur through ingestion of tobacco or other products containing nicotine (such as pesticides or nicotine-replacement medications) or through absorption of nicotine through the skin, either …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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