AllPosts – Page 236 – PoisonSense

BETA-RECEPTOR BLOCKERS

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology Beta-blockers act as competitive inhibitors of catecholamines at both central and peripheral receptors. Blockade of beta-receptors results in decreased production of intracellular cAMP which in turn suppresses multiple metabolic …

VITAMIN K ANTAGONISTS

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology Superwarfarins such as brodifacoum, bromadiolone, chlorophacinone, difenacoum and difethialone are long acting, odourless, tasteless and colourless hydroxycoumarin rodenticides. They affect regeneration of Vit K. Reduced vitamin K (hydroquinone) is a …

ANTIHISTAMINES

October 30, 2017March 17, 2025 - by Poison Sense

Toxicology Antihistamines (H1 receptor antagonists) are commonly found in medications used for motion sickness, control of allergy-related itching and sleep aids. H1 blocker antihistamines are structurally related to histamine and inhibit the …

NAPTHOQUINONE

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology The possible mechanisms of naphthoquinone-induced toxicity is through extensive depletion of intracellular glutothion (GSH). Dicoumarol compound potentiates its cytotoxicity. Depletion of GSH results from the propensity for naphthoquinones to …

QUINAZOLINE INSECTICIDES

October 24, 2017June 8, 2023 - by Poison Sense

Toxicology includes Pyrifluquinazon and Fenazaquin Fenazaquin is moderately acutely toxic (LD50 134-138 mg/kg ) (EPA, 2007) Most of ingested fenazaquin is excreted primarily in the feces and a little in …

IMINOSTILBENE DERIVATIVE

October 23, 2017June 8, 2023 - by Poison Sense

Toxicology Cabamazepne is an antiepileptic drug also used for treatment of trigeminal neuralgia, and bipolar affective disorder. Its absorption is erratic with a peak plasma levels in 4-8 hours postingestion. …

Featured / First Aid

Basic first aid for the eye and skin

October 9, 2017October 25, 2017 - by PoisonSense

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Non-Specific Management / Poison Management

Clinical management of acute poisoning

October 9, 2017January 7, 2025 - by PoisonSense

If the patient presents early (less than 1 hr post ingestion), induce vomiting safely by ensuring the head is lower than the hips (Hansen and Feilberg, 1998) Administer activated charcoal …

Acute Toxic Agents / Common Name

Fenazaquin

October 9, 2017June 10, 2023 - by PoisonSense

• Fenazaquin is moderatelyacutely toxic (LD50 134/138 mg/kg ) (EPA, 2007) • Most of ingested fenazaquin is excreted primarily in the excreta and a little in the urine, mostly as …