PYRAZOLE INSECTICIDES
Toxicology • Moderate oral toxicity was observed in rats and mice, with LD50 values ranging from 245 to 520 mg/kg bw(IPCS INCHEM) • Fenpyroximate and tebufenpyrad are well absorbed in …
Read MoreChemical Class
This is the category based on a number of factors including chemical structure or the mechanism of action or toxicity.
INFORMATION that is provided includes the toxicology of the compounds in this class, as well as the clinical manifestations and management of acute toxicity.
AVERMECTINS
Toxicology Macrocyclic lactones (macrolides) include 2 groups: avermectins and milbemycins, which were first isolated in 1975 from Streptomyces avermitilis isolated from the soil. Eight different structures were isolated and divided …
Read MoreTHIADIAZINE
Toxicology • Applaud was not very toxic, irritating or caused skin sensitization following acute exposures in laboratory animals Clinical Manifestation • Depression (Env. Health & Toxicology, 2008) • Muscular in-coordination …
Read MoreANTICHOLINERGIC PLANTS
Toxicology • Most plants with anticholinergic properties are from the family Solanaceae, and can be identified from their characteristic flowers. The Solanaceae family is rich in alkaloids that can cause …
Read MoreNEREISTOXIN ANALOGUES
Toxicology • They are selective, stomach acting with some contact action (PPDB, 2015). • Nereistoxins were initially thought to produce a postsynaptic nicotinic acetylcholine receptor anatagonist activity which can lead …
Read MoreTRIAZOLOPYRIMIDINE HERBICIDES
Toxicology • Triazolopyrimidine herbicides include cloransulam-methyl, diclosulam, florasulam-methyl, flumetsulam, and metosulam • The acute oral toxicity is very low (US EPA, 1997;The veterinary Merck manual, 2014). • Cloransulam-methyl was shown …
Read MoreTOXIC ALCOHOLS
Toxicology • Glycol Ether is a chemical used mainly in nail polish removers, products to treat leather, anti-icing agents and as an industrial solvent • Ethylene glycol is metabolised by …
Read MoreMINERAL ACIDS AND BASES
Toxicology They are caustics as they cause damage on contact with tissue surfaces Caustic chemicals produce tissue injury by altering the ionized state and structure of molecules. In aqueous solutions, …
Read MorePYRIDAZINONE
Toxicology • The acute toxicity profile of pyridaben is moderate to low (LD50 570-1350mg/kg) (Igarashi and Sakamoto, 1994) The mechanism of action is thought to be inhibition of electron transport …
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