Toxicology
• Applaud was not very toxic, irritating or caused skin sensitization following acute exposures in laboratory animals
Clinical Manifestation
• Depression (Env. Health & Toxicology, 2008)
• Muscular in-coordination (Env. Health & Toxicology, 2008)
• Abdominal enlargement (Env. Health & Toxicology, 2008)
• Irritation of the respiratory system (Env. Health & Toxicology, 2008)
• Hepatotoxicity
• Thyrotoxicity
Clinical Management
• Treatment should be symptomatic and supportive.
• Establish a patent airway (National Center for Biotechnology Information, 2015).
• Suction if necessary(National Center for Biotechnology Information, 2015).
• For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can . . .
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