Informative.Awareness
Toxicology The most severe adverse effects of fluoroquinolones (FQs) include toxicities of the gastrointestinal tract, central nervous system, cardiovascular system, and musculoskeletal system. The commonest adverse events are gastrointestinal tract …
Read MoreToxicology • Clofentezine is an acaricide with low mammalian toxicity (Oral LD50 > 5000 mg/kg)(IPCS, 2005;AAKO, 2006). • Its mode of toxicity is not understood(IPCS, 2005). • At high doses …
Read MoreToxicology • The mammalian pharmacokinetic studies showed that prothioconazole was rapidly and extensively (> 90%) absorbed from the gastrointestinal tract, the tmax being 0.1–0.7hrs(FAO;D.B. McGregor DB and Soleck R, 2008;National …
Read MoreToxicology • Carbamates include methomyl,pirimicarb carbofuran, aldicarb They are clinically similar to but chemically different from organophosphates. Carbamate insecticides, like the OP insecticides, inhibit AChE and elicit cholinergic hyperstimulation. However, …
Read MoreToxicology • Just like triazine, triazinone inhibit aliphatic amino acid synthesis in plants, a non-existent pathway in mammalian species hence a generally low degree of mammalian toxicity of the technical …
Read MoreToxicology • The trimethyl and triethyltin compounds are well absorbed from the gastrointestinal tract and are the most toxic in this group (Kimbrough R D, 1976). • Some butyltin compounds …
Read MoreToxicology • These herbicides are generally only slightly toxic to freshwater fish and invertebrates, and practically nontoxic to wildfowl and other mammals (Kegley et al, 2014) • Sulfonylureas inhibit the …
Read MoreToxicology Members of this family include atrazine, hexazinone, metribuzin, prometon, prometryn and simazine. Amitrole, is a triazine herbicide thas is reportedly goitrogenic in a number of animal species. Amitrole reduces thyroid …
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