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Acute Toxic Agents

These are toxicants that cause severe to moderately severe adverse effects on single exposure. The effects are oftentimes seen within hrs or few days after exposure.

Acute Toxic Agents / Chemical Class / Specific Management

PYRIPROXYFEN

November 8, 2017February 18, 2026 - by Poison Sense

. Toxicology In a study carried out in rats, pyriproxifen was excreted predominantly in the faeces (90%) (IPCS, 1999) A further study showed almost half of the ingested pyriproxyfen was …

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Acute Toxic Agents / Chemical Class / Specific Management

HYDROCARBONS

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology Hydrocarbons have been broadly classified into two types based on their clinical effects: 1) Hydrocarbons with predominantly aspiration potential: clinical effects are typically limited to direct pulmonary damage and subsequent …

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Acute Toxic Agents / Chemical Class / Specific Management

ORGANOSULPHITE

November 8, 2017June 9, 2023 - by Poison Sense

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Acute Toxic Agents / Chemical Class / Specific Management

CHLOROPICRIN

November 7, 2017June 9, 2023 - by Poison Sense

 Toxicology • Undiluted chloropicrin is highly toxic by ingestion or direct contact with the skin or eyes(E X T O X N E T, 2015) . • It is a …

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Acute Toxic Agents / Chemical Class / Specific Management

RABIES BITE

November 7, 2017April 10, 2025 - by Poison Sense

Toxicology • Some pathogens may be introduced into dog bite injuries such as pasteurella multocida, staphylococci, streptococci and anaerobes. In immunosuppressed patients such as persons on corticosteroid therapy, HIV/AIDS patients, …

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Acute Toxic Agents / Chemical Class / Specific Management

NEONICOTINOID

November 7, 2017September 19, 2024 - by Poison Sense

  Toxicology A new class of insecticide with limited toxicological information in humans. Their actions are more selective to insects, with comparatively less acute toxicity to mammals (Roberts and Reigart, …

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Acute Toxic Agents / Chemical Class / Specific Management

DITHIOCARBAMTES

November 7, 2017April 1, 2025 - by Poison Sense

Toxicology Dithiocarbamates are considered as fungicides of low toxicity. They inhibit SH-containing enzymes and cause dermatitis, conjunctivitis, rhinitis, pharyngitis and bronchitis in humans The dithiocarbonates’ general structure (R1R2)N-(C=S)-SX, where R can be …

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Acute Toxic Agents / Chemical Class / Specific Management

OXADIAZINE

November 7, 2017October 27, 2025 - by Poison Sense

Toxicology In plants these herbicides inhibit protophorphyrinogen oxidase (Protox), leading to accumulation of protoporphyrinogen (protogen). Protogen is oxidized to protoporphyrin IX (which is activated by light and causes formation of …

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Acute Toxic Agents / Chemical Class / Specific Management

BENZENOIDS

November 7, 2017December 15, 2025 - by Poison Sense

Toxicology • Metalaxyl is a slightly toxic compound in EPA toxicity class III (oral LD50 in rats is 669 mg/kg) (E X T O X N E T, 1996) • …

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Acute Toxic Agents / Chemical Class / Specific Management

OXYACETAMIDE

November 7, 2017June 9, 2023 - by Poison Sense

Toxicology • Acute toxicity studies have not been performed on this formulationt as formulated. • The median acute toxic level in rats varies according to sex from 371 mg/kg-1365 mg/kg …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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