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Chemical Class

This is the category based on a number of factors including chemical structure or the mechanism of action or toxicity.
INFORMATION that is provided includes the toxicology of the compounds in this class, as well as the clinical manifestations and management of acute toxicity.

Acute Toxic Agents / Chemical Class / Specific Management

PTHALIC ACID DIAMIDE

February 19, 2018June 9, 2023 - by Poison Sense

Toxicology Pthalamide is an amide. Low toxicity to mammals (Zhou  et al., 2017). Amides/imides react with azo and diazo compounds to generate toxic gases (National Center for Biotechnology Information 2018). …

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Acute Toxic Agents / Chemical Class / First Aid

FLubendiamide

February 19, 2018June 10, 2023 - by Poison Sense

First AIDPre-hospital First AidFirst Aid FaieChemical class: Pthalic acid Diamide Functional class: Insecticide Flubendiamide is a ryanodine receptor agonist, which activates calcium release channels in insect neurons. Has a low …

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Acute Toxic Agents / Chemical Class

Anthranilic Diamide

February 19, 2018June 10, 2023 - by Poison Sense

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Acute Toxic Agents / Chemical Class / Specific Management

PHOSPHONATES

November 9, 2017April 1, 2026 - by Poison Sense

 Toxicology  The mechanism of toxicity of glyphosate in mammals is unknown, but may be the uncoupling of oxidative phosphorylation (Beswick and Millo, 2011). Mechanisms of toxicity of glyphosate formulations are …

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Acute Toxic Agents / Chemical Class / Specific Management

PARACETAMOL

November 9, 2017June 9, 2023 - by Poison Sense

Toxicology Paracetamol is rapidly absorbed from the small intestine (Peak serum conc within 1–2 hrs for standard tablet and within 30 minutes for liquid preparations (Ministry of Health of Singapore, …

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Acute Toxic Agents / Chemical Class / Specific Management

Beta-KETONITRILE

November 9, 2017December 15, 2025 - by Poison Sense

Toxicology • Beta-ketonitriles includes Cyenopyrafen, Cyflumetofen. Beta-ketonitrile group is highly selective and causes poisoning through inhibition of the mitochondrial electron transport complex II enzyme within mite cells. Since complex II, …

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Acute Toxic Agents / Chemical Class / Specific Management

CYCLOHEXENONE DERIVATIVES

November 9, 2017December 15, 2025 - by Poison Sense

Toxicology The cyclohexanediones has-been shown to inhibit lipid biosynthesis in plants possibly through inhibition of acetyl-CoA carboxylase involved in fatty acid synthesis (Secor and Cseke, 1988). Cyclohexanediones includes alloxydim butroxydim …

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Acute Toxic Agents / Chemical Class / Specific Management

HYDROGEN CYANIDE

November 9, 2017May 4, 2025 - by Poison Sense

Toxicology Hydrogen cyanide, a highly volatile, colourless, and extremely poisonous liquid (boiling point 26° C). Hydrogen cyanide and its compounds are used for many chemical processes, including fumigation, the case …

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Acute Toxic Agents / Chemical Class / Specific Management

SILICON

November 9, 2017June 9, 2023 - by Poison Sense

Toxicology Silicon, does not exist naturally in its pure form but reacts with oxygen and water to form silicon dioxide. Silicon dioxide has two naturally occurring forms: crystalline and amorphous. …

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Acute Toxic Agents / Chemical Class / Specific Management

QUINOLIZIDINE ALKALOID

November 9, 2017December 19, 2025 - by Poison Sense

Toxicology • Cytisine, a tricyclic quinolizidine alkaloid found in Baptisia, Cytisus, Laburnum, and Sophora species, has nicotinelike effects on the gastrointestinal (GI) tract and the central nervous system (CNS). • …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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