Poison Sense – Page 234

THIOUREA

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Thiourea insecticides include chloromethiuron and Diafenthiuron • Diafenthiuron comps indicate low toxicity following single doses of the undiluted product (Oral LD50 = 1950 mg/kg; Dermal LD50 = >4000 …

Fluoroquinolone Toxicity

October 31, 2017March 10, 2026 - by Poison Sense

Toxicology The most severe adverse effects of fluoroquinolones (FQs) include toxicities of the gastrointestinal tract, central nervous system, cardiovascular system, and musculoskeletal system. The commonest adverse events are gastrointestinal tract …

CLOFENTEZINE

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Clofentezine is an acaricide with low mammalian toxicity (Oral LD50 > 5000 mg/kg)(IPCS, 2005;AAKO, 2006). • Its mode of toxicity is not understood(IPCS, 2005). • At high doses …

METHANOL

October 31, 2017October 30, 2026 - by Poison Sense

Toxicology Products that contain methanol include windshield wiper fluid, industrial solvents, some types of antifreeze, carburetor cleaner, copy machine fluid, antiseptics such as methylated spirit, lab-grade alcohol, perfumes, and different …

TRIAZOLINTHIONE FUNGICIDES

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • The mammalian pharmacokinetic studies showed that prothioconazole was rapidly and extensively (> 90%) absorbed from the gastrointestinal tract, the tmax being 0.1–0.7hrs(FAO;D.B. McGregor DB and Soleck R, 2008;National …

CARBAMATES

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Carbamates include methomyl,pirimicarb carbofuran, aldicarb They are clinically similar to but chemically different from organophosphates. Carbamate insecticides, like the OP insecticides, inhibit AChE and elicit cholinergic hyperstimulation. However, …

TRIAZINONE

October 31, 2017June 8, 2023 - by Poison Sense

Toxicology • Just like triazine, triazinone inhibit aliphatic amino acid synthesis in plants, a non-existent pathway in mammalian species hence a generally low degree of mammalian toxicity of the technical …

ORGANOTIN MITICIDES

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology • The trimethyl and triethyltin compounds are well absorbed from the gastrointestinal tract and are the most toxic in this group (Kimbrough R D, 1976). • Some butyltin compounds …

URACIL

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology • Liquid formulations of bromacil are moderately toxic, while dry formulations are relatively non-toxic • Acute oral LD50 of bromacil is 2000 mg/kg (male rats), 1300 mg/kg (female rats) …

SULFONYLUREA

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology • These herbicides are generally only slightly toxic to freshwater fish and invertebrates, and practically nontoxic to wildfowl and other mammals (Kegley et al, 2014) • Sulfonylureas inhibit the …