Author: Poison Sense
PHENYLAMIDES
Toxicology • The cardiotoxic effects is mediated by alpha 1-adrenoreceptor activity since it is blocked by alpha 1-adrenoreceptor antagonist sauch as phentolamine (a nonselective alpha-adrenoreceptor antagonist) and prazosin (an alpha …
Read MoreTHIOCARBAMATES
Toxicology • As a chemical family, the thiocarbamates are a group of pesticides with a wide range of uses. Some are used as fungicides, while others have herbicidal activity (Fishel …
Read MoreBARBITURATES
Toxicology At low doses, barbiturates bind to GABA-sensitive ion channels in CNS, leading increased influx of chloride ions into cell membranes where they produce hyperpolarization of post synaptic neurone (Lafferty …
Read MoreDINITROANILINE
Toxicology • Exposure route is by inhalation of its aerosol, through the skin and by ingestion (National Center for Biotechnology Information, 2015) • Oral exposure to rats showed low toxicity …
Read MoreORGANOCHLORINE
Toxicology • The organochlorine (OCs) insecticides belong to three distinct chemical classes including the dichlorodiphenylethane, chlorinated cyclodiene and chlorinated benzene cyclohexane-related structures (Ecobichon DJ, 2008). • The LD50s of OCs …
Read MoreTRIFLUOROMETHYL AMINOHYDRAZONE
Toxicology • Hydramethylnon acts by disrupting energy production in the cells. It works by inhibiting complex III in the mitochondrial inner membrane and leads to a halting of oxidative phosphorylation. …
Read MoreSUBSTITUTED UREA
Toxicology • The urea-derivatives are typical pre-emergence herbicides applied usually as aqueous emulsions to the surface of soil. Almost all of the urea compounds with good herbicidal action are trisubstituted …
Read MoreSTROBILURINS
Toxicology • Inhibits cytochrome complex and thus antagonizes electron transfer that finally causes inhibition of mitochondrial respiration( Roberts and Reigart, 2013) • They produce relatively low toxicity; most strobilurins report …
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