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Author: Poison Sense

Acute Toxic Agents / Chemical Class / Specific Management

THIADIAZINE

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology • Applaud was not very toxic, irritating or caused skin sensitization following acute exposures in laboratory animals Clinical Manifestation • Depression (Env. Health & Toxicology, 2008) • Muscular in-coordination …

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Acute Toxic Agents / Chemical Class / Specific Management

ANTICHOLINERGIC PLANTS

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology • Most plants with anticholinergic properties are from the family Solanaceae, and can be identified from their characteristic flowers. The Solanaceae family is rich in alkaloids that can cause …

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Acute Toxic Agents / Chemical Class / Specific Management

NEREISTOXIN ANALOGUES

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology • They are selective, stomach acting with some contact action (PPDB, 2015). • Nereistoxins were initially thought to produce a postsynaptic nicotinic acetylcholine receptor anatagonist activity which can lead …

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Acute Toxic Agents / Chemical Class / Specific Management

TRIAZOLOPYRIMIDINE HERBICIDES

November 8, 2017December 12, 2025 - by Poison Sense

Toxicology • Triazolopyrimidine herbicides include cloransulam-methyl, diclosulam, florasulam-methyl, flumetsulam, and metosulam • The acute oral toxicity is very low (US EPA, 1997;The veterinary Merck manual, 2014). • Cloransulam-methyl was shown …

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Acute Toxic Agents / Chemical Class / Specific Management

TOXIC ALCOHOLS

November 8, 2017November 24, 2025 - by Poison Sense

Toxicology • Glycol Ether is a chemical used mainly in nail polish removers, products to treat leather, anti-icing agents and as an industrial solvent • Ethylene glycol is metabolised by …

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Acute Toxic Agents / Chemical Class / Specific Management

MINERAL ACIDS AND BASES

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology They are caustics as they cause damage on contact with tissue surfaces Caustic chemicals produce tissue injury by altering the ionized state and structure of molecules. In aqueous solutions, …

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Acute Toxic Agents / Chemical Class / Specific Management

PYRIDAZINONE

November 8, 2017December 12, 2025 - by Poison Sense

Toxicology • The acute toxicity profile of pyridaben is moderate to low (LD50 570-1350mg/kg) (Igarashi and Sakamoto, 1994) The mechanism of action is thought to be inhibition of electron transport …

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Acute Toxic Agents / Chemical Class / Specific Management

BORATES

November 8, 2017June 9, 2023 - by Poison Sense

Toxicology • Borates exist in both alkaline (sodium borate ie borax) and acid (boric acid) forms • Boric acid has low oral and dermal toxicity. However, in the form of …

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Acute Toxic Agents / Chemical Class / Specific Management

BENZOYLUREA INSECTICIDES

November 8, 2017December 21, 2025 - by Poison Sense

Toxicology • Although the exact mechanism of toxicity is not elucidated, it is thought to inhibit the production of the enzyme chitin synthase during molting of immature stages of arthropods …

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Acute Toxic Agents / Chemical Class / Specific Management

PYRIPROXYFEN

November 8, 2017February 18, 2026 - by Poison Sense

. Toxicology In a study carried out in rats, pyriproxifen was excreted predominantly in the faeces (90%) (IPCS, 1999) A further study showed almost half of the ingested pyriproxyfen was …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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