Informative.Awareness
The household bleach such as Jik used for cleaning and disinfecting contains sodium hypochlorite as the active ingredient. Mixing of sodium hypochlorite with ammonia or acidic agents gives off a …
Read MoreBenzodiazepines (BZD) including diazepam, lorazepam, flunitrazepam and midazolam bind allosterically (binding at a site other than the ligand’s active site) to specific receptors-GABAA receptor-in the central nervous system to enhance …
Read MorePesticides, and even medicines, must be effective to be commercially viable, but importantly, must also be reasonably safe for those who manufacture them, apply them, or take them or the …
Read MoreSodium metabisulphite (aka Sodium Pyrosulphite or Disodium) belong to a family of chemicals known as sulphites. It is white or yellowish-white crystalline powder used as a disinfectant, antioxidant and …
Read MorePesticides are synthesized substances or biological agents used for attracting, destroying, or mitigating any pest. Toxicity of pesticides refers to the ability of a pesticide to produce adverse effects. These …
Read MoreAssociated with impairment of normal cooling mechanisms such as sweating Treatment: Supportive care including active cooling and benzodiazepines NOTE: It is difficult to differentiate the toxic hyperthermic syndromes including hyperthermia …
Read MoreTriad of hyperthermia, muscle rigidity, and metabolic acidosis – Occurs in genetically susceptible individuals (both autosomal dominant and recessive inheritance patterns) – Triggered by general anaesthetics (volatile gases, succinylcholine) – …
Read MoreIt is an idiosyncratic reaction (not related to dose or duration) to certain medications, mostly neuroleptics, within 7 days (4 weeks with depot preparations). Mechanisms Pathophysiology most likely includes acute …
Read MoreSympathomimetic fever Sympathomimetics, such as amphetamines and cocaine, may produce hyperthermia due to excess serotonin and dopamine resulting in thermal deregulation Treatment is supportive including active cooling and benzodiazepine Uncoupling …
Read MoreHyperthermia is defined as an uncontrolled rise of core body temperature above 38°C, at which temperature the human body is unable to lose heat. In drug induced hyperthermia, the core …
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