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PoisonSense Blog

PoisonSense Blog

WHY TINIDAZOLE IS A SUPERIOR DRUG COMPARED TO METRONIDAZOLE 

June 13, 2023 - by Poison Sense

1. Tinidazole’s long half-life allows for a convenient once a day administration 2. Tinidazole is effective against metronidazole- resistant organisms 3. Tinidazole has a relatively favourable toxicity profile compared with …

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PoisonSense Blog

HOW TO DEWORM CORRECTLY

June 13, 2023 - by Poison Sense

The correct way to take by mouth a dewormer is dependent on the location of the target organism. The absorption of albendazole and mebendazole are enhanced by fatty meals. Thus, …

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PoisonSense Blog

WHY NITAZOXANIDE IS A BETTER ANTIPROTOZOAL

June 13, 2023 - by Poison Sense

It is active against metronidazole resistant protozoal strains including E. Hystolitica,H pylori, Giardia lamblia and cryptosporidium parvum. It is safer in pregnancy: No teratogenicity or fetotoxicity was observed in animal …

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PoisonSense Blog

WHY DIAZEPAM IS AN IMPORTANT ADJUNCT IN OPP Rx

June 13, 2023 - by Poison Sense

1. Management of organophosphate -induced convulsions 2. Sedation of OP-induced anxiety 3. Amelioration of muscle OPP-induced fasciculation 3. Neuroprotective and may protect against organophosphate-induced central respiratory depression #Thursdaybit #37days2CBA . …

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PoisonSense Blog

JUST AS THERE ARE PRODRUGS, THERE ARE PROPOISONS

June 13, 2023June 13, 2023 - by Poison Sense

Certain poisons are harmless until they are biotransformed in the body to active metabolites. What are their properties? 1. They exhibit a delayed onset of action. A latent period for …

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TREATMENT OF PYRETHROID POISONING

June 13, 2023 - by Poison Sense

Treatment of poisoning caused by pyrethroids is informed by their mechanism of action. Pyrethroids increase neuronal excitability by not only affecting the ubiquitous voltage- sensitive sodium channels but also by …

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WHY IT IS IMPORTANT TO KNOW THE TOXICOLOGY OF A TOXIC AGENT

June 13, 2023 - by Poison Sense

1. GIT AND SKIN ABSORPTION: If it is well absorbed dermally, the skin must be promptly washed with clean water. If it is poorly absorbed orally, activated charcoal and saline …

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WHY HEPARIN IS TRANSIENTLY USED IN WARFARIN THERAPY

June 13, 2023 - by Poison Sense

Warfarin- mediated hemostasis is achieved by the balance of inhibition of procoagulant factors VII, IX, X, and II, and anticoagulant factors C. The half-Life of anticoagulant factors C is shorter …

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WHY LOW DOSE ASPIRIN IS USED TO PREVENT THROMBOTIC EVENTS 

June 13, 2023 - by Poison Sense

Thromboxane A2 is a prostaglandin involved in the clotting process through platelet aggregation and amplifying the effects of thrombin Thromboxane A2 is the major synthetic products of cyclooxygenase-1 ( COX-1) …

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PoisonSense Blog

FACTS ABOUT A POPULAR ACARICIDE IN THE NORTHRIFT; DUODIP

June 13, 2023 - by Poison Sense

“Duo” means two. The acaricide has two insecticidal components;organophosphates and pyrethroids. Chlorpyrifos (organophosphate) acts independently and synergistically with cypermethrin (pyrethroid). The symptoms of Duodip poisoning is dependent largely on the …

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Popular Posts

  • Duodip 55%EC Chemical Class: Organophosphate and Pyrethrin and Pyrethroid Common Chemical Name: Chlorpyrifos and...
  • Tinga Tinga 380 SC Chemical Class: Triazine Common Chemical Name: Atrazine 380 g/L Functional Class: Herbicide
  • Halothrin 2.5EC Chemical Class: Pyrethroid Common Chemical Name: Lambda cyhalothrin 25g/L Functional Class: Insectic...
  • Weedal 480 SL First aid: Weedal 480SL Chemical Class: Phosphonates Common Chemical Name: Glyphosate IPA salt Funct...
  • Genomite 200 EC Chemical Class: Pyridazinone Common Chemical Name: Pyridaben 20% w/v Functional Class: Insecticide
  • Alpha cymba 10 EC Chemical Class: Pyrethroid Common Chemical Name: Alpha-cypermethrin 100g/L Functional Class: Insecti...
  • Waduduklin 25EC Chemical Class: Pyrethroid Common Chemical Name: Lambda cyhalothrin 25g/L Functional Class: Insectic...

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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