WHY WE GIVE ETHANOL FOR METHANOL POISON!
The enzyme that digests methanol to poisonous products that then burns your sense of sight, loves ethanol 200 times more than it does methanol. Ethanol is therefore taken to keep …
Read MorePoisonSense Blog
WHY a single dose gentamycin is more EFFICACIOUS and SAFER
Bactericidal effects of gentamicin is concentration-dependent i.e. the higher the concentration in contact with a susceptible bacteria, the more the killing power. The ototoxic and nephrotoxic effects is time-dependent. Prolonged …
Read MoreARE YOU AWARE THAT THE CHEMICAL STRUCTURE PREDICTS THE PRIMARY ROUTE OF EXCRETION USEFUL IN DETOX?
Knowledge of route and extent of elimination of parent drugs or its active metabolites is critical to successful poison management Drugs or toxicants with high molecular weights (MW ≥ 400 …
Read MoreSELF-POISONING AND ALCOHOL WITHDRAWAL
Anecdotal evidence show that a significant number of deliberate self-poisoning victims are also alcohol dependent (ie continued alcohol drink, despite problems with health, and, family, or job responsibilities) Recognition and …
Read MoreSUPERWARFARIN RODENTICIDES
It’s very important to know at the outset that not all rodenticides are anticoagulants. For example, the commonly abused rodenticide Rat and Rat is a zinc phosphide rather than a …
Read MoreEpidemiology and Toxicology
Understanding the epidemiology of poisoning assists in developing effective treatment and prevention strategies aimed at reducing morbidity and mortality. The predominant causative agent in a particular functional group of pesticides …
Read MoreHow Toxicity to Amphotericin-B Is Mitigated
Adverse Effects About 80% of the patients will develop infusion-related adverse effects or nephrotoxicity. Hypokalemia Hypomagnesemia Anaphylaxis Nephrotoxicity: Renal toxicity correlates with conventional amphotericin B use. But the azotemia often …
Read MoreFUNGICIDE PESTICIDES AND ALCOHOL
Some fungicides such as Oshothane, Master 72,Tower 72,Milthane super,D-thane 45 of dithiocarbamate class, used in agricultural pest control activities block the efficient degradation of ethanol (inhibits CYPE1) thereby promoting accumulation …
Read MoreVX NERVE AGENT
Kim Jong Nam the elder brother to North Korean president was assassinated in Malaysia using a VX nerve agent wiped on his face. So, what is VX? VX is a …
Read MoreWhat should you know about fluoroquinolones?
1. That though it causes damage to growing cartilage, the damage is reversible. Fluoroquinolones may therefore be used in children in some conditions 2. That tendonitis increases the risk of …
Read More