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Chemical Class

This is the category based on a number of factors including chemical structure or the mechanism of action or toxicity.
INFORMATION that is provided includes the toxicology of the compounds in this class, as well as the clinical manifestations and management of acute toxicity.

Acute Toxic Agents / Chemical Class / Specific Management

URACIL

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology • Liquid formulations of bromacil are moderately toxic, while dry formulations are relatively non-toxic • Acute oral LD50 of bromacil is 2000 mg/kg (male rats), 1300 mg/kg (female rats) …

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Acute Toxic Agents / Chemical Class / Specific Management

SULFONYLUREA

October 30, 2017June 8, 2023 - by Poison Sense

 Toxicology • These herbicides are generally only slightly toxic to freshwater fish and invertebrates, and practically nontoxic to wildfowl and other mammals (Kegley et al, 2014) • Sulfonylureas inhibit the …

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Acute Toxic Agents / Chemical Class / Uncategorized

DIACYLHYDRAZINES

October 30, 2017December 17, 2025 - by Poison Sense

Toxicology • Tebufenozide Technical is reportedly practically non-toxic by ingestion of a single oral dose in rats and mice (LD50 > 5,000 mg/kg and was practically non-toxic by dermal application …

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Acute Toxic Agents / Chemical Class / Specific Management

TRIAZINE HERBICIDES

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology Members of this family include atrazine, hexazinone, metribuzin, prometon, prometryn and simazine.  Amitrole, is a triazine herbicide thas is reportedly goitrogenic in a number of animal species. Amitrole reduces thyroid …

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Acute Toxic Agents / Chemical Class / Specific Management

CHLOROACETANILIDE HERBICIDES

October 30, 2017April 24, 2025 - by Poison Sense

Toxicology The commonly used herbicides are alachlor, acetochlor, butachlor, metolachlor, and propachlor. This class of herbicides is slightly hazardous, except butachlor, which is not likely to pose any hazard. Chloroacetanilides …

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Acute Toxic Agents / Chemical Class / Specific Management

SAFROLE

October 30, 2017January 2, 2026 - by Poison Sense

Toxicology • The major target organ of piperonyl butoxide(PBO) is the liver.Histopathological effects including enlargement of hepatocytes with glassy cytoplasm, oval cell proliferation, bile duct hyperplasia, and focal necrosis were …

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Acute Toxic Agents / Chemical Class / Specific Management

BETA-2 RECEPTOR AGONISTS

October 30, 2017June 8, 2023 - by Poison Sense

 Toxicology Beta-2 adrenergic agonists includes Bitolterol, Formoterol, Metaproterenol, Pirbuterol, Salbutamol (Albuterol), Salmeterol, Terbutaline among others • beta-2receptor agonists causes increased heart rate in sinoatrial node (SA node) in addition to …

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Acute Toxic Agents / Chemical Class / Specific Management

BENZONITRILE HERBICIDES

October 30, 2017December 12, 2025 - by Poison Sense

 Toxicology • Some nitriles such as Bromoxynil Octanoate are moderately acutely toxic (Oral LD50, 50-500 mg/kg) (Kegley et al 2014). • The principal toxic action of the benzonitriles eg Bromoxynil …

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Acute Toxic Agents / Chemical Class / Specific Management

CHLOROPHENOXY COMPOUNDS

October 30, 2017December 12, 2025 - by Poison Sense

Toxicology Chlorophenoxy herbicides contain an aliphatic carboxylic acid moiety attached to a chlorine-or-methyl-substituted aromatic ring. Representative compounds of this class include 2,4-dichlorophenoxy acetic acid; 2, 4-dichlorophenoxy propionic acid; 2,4,5-trichlorophenoxy acetic …

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Acute Toxic Agents / Chemical Class / Specific Management

COPPER SALTS & ORGANIC COMPLEXES

October 30, 2017June 8, 2023 - by Poison Sense

Toxicology • Copper sulphate is a powerful oxidizing agent and a corrosive acid to mucous membranes (Saravu et al 2007). • The soluble copper salts such as CuSO4 show limited …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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