Hyperthermia is defined as an uncontrolled rise of core body temperature above 38°C, at which temperature the human body is unable to lose heat.
Chemical-induced hyperthermia is a hypermetabolic state caused by medications and other agents that alter neurotransmitter levels (Musselman et al., 2013).
Non-infective causes of hyperthermia include heat illness and drug-induced hyperthermia
Mechanisms
The mechanism of action responsible for many types of poison-induced fevers is not understood.
Dysfunction of the thermoregulatory system is one of many pathologies documented in experimental animals and humans exposed to toxic chemicals (Gordon et al., 1998).
Possible causes . . .
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