Hyperthermia is defined as an uncontrolled rise of core body temperature above 38°C, at which temperature the human body is unable to lose heat.
In drug induced hyperthermia, the core temperature is at least 38.3°C
DIH syndromes can be fatal if not recognized promptly and managed appropriately.
There are five major DIH syndromes: (1) neuroleptic malignant syndrome, (2) serotonin syndrome, (3) anticholinergic poisoning, (4) sympathomimetic poisoning, and (5) malignant hyperthermia.
The differential diagnosis of DIH syndromes can be challenging because symptoms are generally nonspecific, ranging from blood pressure changes and excessive sweating to altered mental status, muscle . . .
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