Rational Selection of Vasopressors: which, when, and how much?

In addition to definitive airway management, hemodynamic support is among the most important life-saving interventions.
Fluids first
Fluid administration is the first-line therapy, which aims at correcting hypotension and low blood flow related to both relative and absolute hypovolemia (Shi et al., 2020). Initial fluids (30 mL/kg initially and more as needed) should be crystalloid.
Vasopressors
According to Surviving Sepsis Campaign (SSC) and European Society of Intensive Care Medicine (ESICM) vasopressors should be administered as soon as possible especially when fluid administration is not sufficient to achieve the desired mean arterial pressure (MAP). Early vasopressors prevent and . . .

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