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Poison Management

Non-Specific Management

Poison Associated Acute Pulmonary Edema

July 9, 2019July 2, 2025 - by Poison Sense

Pulmonary edema is an abnormal accumulation of extravascular fluid in the lung parenchyma leading to diminished gas exchange at the alveolar level. The accumulation of fluids in the lungs may …

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Non-Specific Management

Poison Induced Seizures/ Agitation

July 9, 2019January 7, 2025 - by Poison Sense

• Rule out hypoglycemia using bed side random blood sugar (Green et al 2005) • In repeated seizures, benzodiazepines are the drug of choice. With benzodiazepines therapy one should be …

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Non-Specific Management

Hypoglycemic Crisis

July 9, 2019January 7, 2025 - by Poison Sense

CLINICAL MANIFESTATION • Serum glucose less than 3.3mmol/dl • All patients presenting with altered mentation should get a bedside blood glucose measurement • Overdose with long acting insulin such as …

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Non-Specific Management

Alcohol Withdrawal Syndrome

July 9, 2019January 7, 2025 - by Poison Sense

Pathophysiology The severity of alcohol withdrawal symptoms are thought to result from genetic predisposition, the amount of alcohol taken daily and the duration of sustained ethanol use. Acute alcohol intoxication …

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Non-Specific Management

Hyperglycemia Hyperosmolar State

July 9, 2019May 20, 2025 - by Poison Sense

PATHOPHYSIOLIOLOGY. • Absolute or relative insulin deficiency causes inadequate control of blood glucose concentration leading to severe hyperglycemia, which overwhelms renal glucose homeostasis. CLINICAL MANIFESTATION. • Hyperglycemia with insignificant ketoacidosis …

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Non-Specific Management

1. Poison Induced Hypersecretory State

July 9, 2019 - by Poison Sense

Administer Iv atropine in cases of excess bronchial secretions associated with bradycardia Give in an age dependent dose as follows: ˂2 yrs: IV 0.02mg/kg q5min 2-10 yrs: IV 1-2mg q …

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Acute Toxic Agents / Chemical Class / Specific Management

SALICYLANILIDE ANTHELMINTIC

June 18, 2019May 16, 2024 - by Poison Sense

The molecular mode of action of halogenated salicylanilide, including closantel, niclosamide,oxyclozanide, rafoxanide and resorantel is not completely elucidated. Salicylanilides, also referred to as benzamides or salicylamides, are weak,acidic phenolic compounds (Swan …

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Acute Toxic Agents / Chemical Class / Specific Management

DICHLOROACETAMIDE safeners

June 15, 2019December 10, 2025 - by Poison Sense

Toxicology Safeners are agrochemicals that protect crops from herbicide toxicity. Dichloroacetamide safeners (e.g., AD-67, benoxacor, dichlormid, and furilazole) are co-applied with chloroacetanilide herbicides to protect crops from herbicide toxicity Their …

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Acute Toxic Agents / Chemical Class / Specific Management

PYRIMIDINYL CARBOXY HERBICIDE

June 10, 2019December 22, 2025 - by Poison Sense

Toxicology Pyrimidinylthiobenzoates This family includes bispyribac-sodium, pyrithiobac-sodium,pyriminobac-methyl Adjuvants such as non-ionic surfactants and petroleum based oils may be added to improve herbicidal efficacy The mode of action has been considered …

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Acute Toxic Agents / Chemical Class / Specific Management

BENZOYLPYRAZOLE

June 4, 2019December 21, 2025 - by Poison Sense

Toxicology Pyrazolinate, Pyrazoxifen, Benzofenap, Topramezone and Pyrasulfotole are so far the benzoylpyrazole introduced into the herbicide market. These compounds inhibit 4-hydroxyphenylpyruvate dioxygenase (HPPD) n plants and animals. HPPD is an …

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
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