CYCLOHEXENONE DERIVATIVES

Toxicology
The cyclohexanediones has-been shown to inhibit lipid biosynthesis in plants possibly through inhibition of acetyl-CoA carboxylase involved in fatty acid synthesis (Secor and Cseke, 1988).
Cyclohexanediones includes alloxydim butroxydim clethodim cycloxydim profoxydim sethoxydim tepraloxydin tralkoxydim.
• Tralkoxydim is efficiently absorbed and rapidly excreted in rats and hamsters (California Environmental Protection Agency, 1999)
• The dominant initial route of excretion is in the bile but subsequent extensive entero-hepatic recirculation leads to more than 50% of tralkoxydin to be exceted in urine(California Environmental Protection Agency, 1999)
• The dominant metabolite excreted is tralkoxydim acid which could also be used as . . .

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