PYRIPROXYFEN

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Toxicology

  • In a study carried out in rats, pyriproxifen was excreted predominantly in the faeces (90%) (IPCS, 1999)
  • A further study showed almost half of the ingested pyriproxyfen was excreted unabsorbed, suggesting gut decontamination methods such as catharsis and activated charcoal may be effective (IPCS, 1999)
  • In another study in Sprague-Dawley rats, the peak concentration of radiolabeled pyriproxyfen in blood was observed 8 hrs after dosing, which was four-six times higher in males (IPCS, 1999)
  • At peak blood level of pyriproxyfen, the highest tissue concentration was observed in the liver . . .

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