Toxicology
• The organochlorine (OCs) insecticides belong to three distinct chemical classes including the dichlorodiphenylethane, chlorinated cyclodiene and chlorinated benzene cyclohexane-related structures (Ecobichon DJ, 2008).
• The LD50s of OCs are typically between 130-400 mg/kg (Sánchez-Bayo F, 2011)
• Bridged diphenyl acaricides such as tetradifon, are more or less structurally related to DDT(an organochlorine)
• Liver and kidney in rats and liver in mice are the major target organs (Chhabra et al, 2001) • The estimated toxic dose is 10 g/kg bwt.
• The chlorinated cyclodiene insecticides are among the most toxic and environmentally persistent pesticides.
Dichlorodiphenylethane
• DDT
• DDD . . .
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