DIACYLHYDRAZINES

Toxicology
• Tebufenozide Technical is reportedly practically non-toxic by ingestion of a single oral dose in rats and mice (LD50 > 5,000 mg/kg and was practically non-toxic by dermal application and causes slight skin irritation and skin sensitisation and moderate eye irritation(LD50 > 5,000 mg/kg) (ENVIRONMENTAL PROTECTION AGENCY, 1998;USDA,Forest Service Forest :Health Protection, 2004;Australian Pesticides and Veterinary Medicines Authority)
• A study in laboratory animals (mice rata and dog)show that the principal mechanism of tebufenozide toxicity involves the blood thereby causing increased erythrocytic turnover and compensatory hematopoiesis (USDA,Forest Service Forest . . .

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