BIPYRIDYL HERBICIDES

Toxicology

  • Bipyridyl (or bipyridinium) herbicides are quaternary ammonium compounds marketed as contact herbicides and desiccants (Eddleston M. 2016).
  • Bipyridyl herbicides-diquat and paraquat-exist as divalent cations found as dibromide or dichloride salts, respectively.
  • Paraquat has one of the highest acute toxicities among herbicides; its oral LD50 in rat is about 100 mg/kg. In humans as little as 10-15 mL of a 20% solution is toxic (Costa GL 2008; Roberts and Reigart, 2013).
  • From one Sri Lankan population analysis on paraquat, there appears to be a clearance of 1.17 . . .

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