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Author: Poison Sense

PoisonSense Blog

TOXIC OVERDOSE EFFECTS OF ANTIEPILEPTICS , TRICYCLIC ANTIDEPRESSANTS AND ANTIPSYCHOTICS.

June 13, 2023 - by Poison Sense

Antiepileptics such as carbamazepine; Tricyclic antidepressants such as amitriptiline; and most antipsychotics cause blockade of voltage gated sodium channels in the heart associated with QT wave prolongation. The ECG changes …

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PoisonSense Blog

TREATMENT OF ALFA- GLUCOSIDASE INHIBITOR OVERDOSE 

June 13, 2023 - by Poison Sense

Alfa- glucosidase inhibitors such as Acarbose, Miglitol and Voglibose that act on the gastrointestinal tract to interfere with carbohydrate digestion are used as oral antidiabetics. An overdose from these drugs …

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PoisonSense Blog

MERCURY POISONING IN GOLD MINES

June 13, 2023 - by Poison Sense

Elemental mercury is used by artisanal and small-scale miners in gold production in gold mines in Migori and other areas in western Kenya. The pattern of clinical intoxication from mercury …

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PoisonSense Blog

THE TOXICOLOGY OF ALCOHOL

June 13, 2023 - by Poison Sense

Alcohol is a small water soluble molecule that’s absorbed rapidly from the gastrointestinal tract but whose absorption is delayed by presence of food in the stomach. Because of its relative …

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PoisonSense Blog

HOW TO PREVENT SNAKE BITE

June 13, 2023June 13, 2023 - by Poison Sense

The majority of snakes are fearful of humans and would rather flee than confront people. However, if a snake feels threatened they will bite. You can prevent the majority of …

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PoisonSense Blog

THE TRUTH ABOUT SHISHA SMOKING  

June 13, 2023 - by Poison Sense

Shisha smoke, just as cigarette smoke contains toxic agents such as nicotine, carbon monoxide, heavy metals, tar and cancer-causing chemicals like benzene. Although some nicotine is absorbed by water in …

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PoisonSense Blog

INDICATIONS FOR ANTIVENOM

June 13, 2023July 27, 2025 - by Poison Sense

Antivenoms are relatively costly (about ksh. 5000/10mls vial), oftentimes in short supply, but with an inherent risk for hypersensitivity reactions. Antivenoms should therefore not be used indiscriminately. Antivenoms are recommended …

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PoisonSense Blog

Detection and management of hyperkalemia

June 13, 2023June 13, 2023 - by Poison Sense

TOXICOLOGY: Compared to hypokalemia, hyperkalemia is a relatively uncommon metabolic complication of poisoning. Hyperkalemia follows inhibition of Na+/K+ ATPase activity (e.g. by digoxin); disruption of intermediary metabolism (e.g. cyanide poisoning); …

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PoisonSense Blog

ANTIEPILEPTIC DRUG

June 13, 2023 - by Poison Sense

In general, the type of drug used for epilepsy depends on the seizure type. Errors in seizure diagnosis often results in the use of inappropriate drug therapy; poor seizure control; …

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PoisonSense Blog

THE COMMONLY MISUSED AND ABUSED FLU MEDICINES

June 13, 2023 - by Poison Sense

Drug abuse is a continuing problem throughout the world. Medicines for flu particularly cough suppressants such as Benylin, Coscof C, Actifed and Betapyn tablets, are often abused by teenagers who …

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Popular Posts

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Hi, I am Dr. Bundo, Msc in pharmacology and Toxicology.
This site is here to bring clinical toxicology information to the public domain.

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