Toxicology
• The chemical and toxicologic properties of chromium differ , depending on the valence state of the metal (Digitalfire Reference database)
• Chromium exists in its metallic state (valence 0), and in valence states 2+ to 6+
• The trivalent (3+) and hexavalent (6+) are commonly found. Naturally occurring chromium compounds are generally in the trivalent state [chromium (III)], while hexavalent chromium compounds [chromium (VI)] are produced industrially by the oxidation of chromium (III) compounds
• Hexavalent chromium is unstable in the body and is reduced intracellularly (by many substances including ascorbate and glutathione). Chromium in 2+ state, 4+ and 5+ states are found . . .
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