DITHIOCARBAMTES

Toxicology

  • Dithiocarbamates are considered as fungicides of low toxicity. They inhibit SH-containing enzymes and cause dermatitis, conjunctivitis, rhinitis, pharyngitis and bronchitis in humans
  • The dithiocarbonates' general structure (R1R2)N-(C=S)-SX, where R can be substituted by an alkyl, alkylene, aryl, or similar other group, and X usually by a metal ion.
  • Their molecules contain a metal atom that determines their name. Thus, there are, for example, Maneb (Mn), Ziram and Zineb (Zn), and Mancozeb (Mn and Zn)
  • They have low acute toxicity but may cause skin sensitization . . .

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