Cellular respiration (oxidative phosphorylation) is the metabolic pathway within the mitochondria used by cells to oxidize nutrients to release free energy which is used to generate free energy which is transformed into high-energy phosphate bonds, ATP (chemical currency of energy).
During oxidative phosphorylation, electrons are transferred through a series of protein complexes I-IV that culminates in oxidation/ reduction of oxygen. These redox reactions release energy, which is used to form ATP.
Mitochondrial poisons affect the integrity and functioning of mitochondria through Inhibition of electron transport chain (ETC) and uncoupling of oxidative phosphorylation. Many medicinal drugs-antiretroviral nucleoside/nucleotide . . .
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