WHY SERUM CREATININE IS A POOR MEASURE IN GERIATRICS

The elderly generally have a reduced muscle mass. Since creatinine is a metabolic product of muscle proteins, the diminished muscle mass in the elderly significantly affect the reliability of serum creatinine as a measure of kidney function

As a matter of fact, there is a poor correlation between serum creatinine and kidney function in the elderly.

Creatinine clearance, instead, is a more precise indicator of kidney function in this population.

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