1. Too rapid administration of drugs having a high volume of distribution results in a transiently toxic blood concentrations that may injure or overstimulate organs such as the heart to cause cardiac arrest e.g. labelol, adrenaline
2. Some drugs cause vasodilation and therefore presents an increased risk for postural hypotension and falls when administered too fast.
Drugs that carry a risk of adverse effects if administered too quickly should be diluted and administered via an infusion pump or syringe pump.
Additionally, drugs that require administration over 1 minute should not be labelled as "IV push" or "IV bolus" but . . .
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