A typical antiretroviral regimen includes a "backbone" of two nucleoside reverse transcriptase inhibitors (NRTI) such as Tenofovir and Lamivudine and a "base" of either a protease inhibitor (PI) (lopinavir, atazanavir etc) or nonnucleoside reverse transcriptase inhibitor (Efavirenz, Nevirapine). Tenofovir Lamivudine Efavirenz (TLE) regimen is such a typical antiviral drug fixed dose combination.
The most serious overdose outcomes have been reported in neonates who were inadvertently administered supratherapeutic doses of HIV prophylaxis medications. However, as the number of HIV/AIDS patients on treatment increases, the suicide rate using HAART medication will be observed more frequently. Clinicians and Toxicologists should be acquainted . . .
Please Subscribe to continue reading
