Ogilvie's syndrome, also known as acute colonic pseudo-obstruction (ACPO), is a paralytic ileus of the colon that is characterized by massive colonic distension in the absence of mechanical obstruction. If left untreated, it may lead to bowel perforation or ischemia.
Ogilvie's syndrome presents with severe tenderness, distension and pain in the abdomen. Patients are unable to pass faeces or flatus through the anus.
Although the underlying pathogenesis of the syndrome is not completely understood, excessive parasympathetic suppression or sympathetic stimulation, or a combination of both is thought to be the cause.
All psychopharmacs with anticholinergic side effects . . .
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