Amitraz is a formamidine derivative that is widely used as a pesticide in the preservation of agricultural products and the control of ectoparasites in animals.
Commercial formulations of amitraz generally contain 12.5–20% of the drug in organic solvents, especially xylene. Therefore, symptoms and signs result from both xylene and amitraz.
Upon intoxication by ingestion, inhalation, or dermal route, it can cause various central nervous system (CNS), CVS, respiratory and gastrointestinal effects, some of which may be life threatening (Pratti et al., 2020).
Due to its lipophilic property, amitraz is rapidly absorbed from the biological membranes.
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