HALOGENATED HYDROCARBONS

Toxicology
• Methyl bromide is highly toxic(ATSDR, 1992). • Methyl bromide is odorless and nonirritating, a lacrimator (an agent that irritates the eyes and causes tearing), chloropicrin, is often added as a warning agent.
• Methyl bromide is absorbed well by the lungs and slightly through intact skin. Oral exposure is rare because methyl bromide is a gas at room temperature.
• Methyl bromide gas easily penetrates most protective clothing (e.g., cloth, rubber, and leather) and skin
• Children are most vulnerable to toxicity because of large skin/lung surface area to weight ratio
• At cellular level, methyl bromide methylates the sulfhydryl groups . . .

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