Toxicology
• Triazolopyrimidine herbicides include cloransulam-methyl, diclosulam, florasulam-methyl, flumetsulam, and metosulam
• The acute oral toxicity is very low (US EPA, 1997;The veterinary Merck manual, 2014).
• Cloransulam-methyl was shown to be practically non-toxic to small mammals with an LD50 > 5000 mg/kg (US EPA, 1997)
• Pyroxsulam has low acute oral (LD50 >2000 mg/kg bw) and dermal (LD50 >2000 mg/kg bwt) toxicity (Central Agricultural Pesticide Laboratory, 2009)
• Pyroxsulam is rapidly absorbed and excreted mostly unchanged in the urine and faeces with the majority of the compound being eliminated by 12 and 24 hr . . .
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