Toxicology
• The cardiotoxic effects is mediated by alpha 1-adrenoreceptor activity since it is blocked by alpha 1-adrenoreceptor antagonist sauch as phentolamine (a nonselective alpha-adrenoreceptor antagonist) and prazosin (an alpha 1-adrenoreceptor antagonist) (Naidu and Radhakrishnamurty, 1989)
Clinical Manifestation
• Bradycardia
• Hypotension and shock
Clinical Management
• For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool (Bronstein and Currance, 1994)
• If a large amount of the fungicide has been ingested in the last few hours, and if severe . . .
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