Carbamazepine is an antiepileptic drug also used in the treatment of neuralgic pain especially trigeminal neuralgia and as a mood stabilizer.
Carbamazepine toxicity is common in the pediatric population attributable to unintentional overdoses. Once swallowed carbamazepine is absorbed slowly but erratically because of its lipophilic nature. Clinical symptoms develops 1-3 hours after ingestion and peaks 4-8 hours after an oral dose but may take up to 72 hours after a large ingestion. Carbamazepine is metabolized primarily in the liver and ultimately excreted in the urine. The presence of active metabolite, carbamazepine-10, 11-epoxide, prolongs duration of the . . .
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