Toxicology
- Members of this family include atrazine, hexazinone, metribuzin, prometon, prometryn and simazine.
- Amitrole, is a triazine herbicide thas is reportedly goitrogenic in a number of animal species. Amitrole reduces thyroid uptake of iodine and inhibits the peroxidase activity of the thyroid hence causing hypothalamus mediated TSH stimulation on the thyroid itself (IPCS, 1998).
- The mechanism of acute triazine herbicide toxicity in humans is not known. it is thought to disturb energy metabolism (thiamin and riboflavin functions) (E X T O X N E T, 1993).
- Triazines have low oral toxicity and . . .
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