Toxicology
Beta-2 adrenergic agonists includes Bitolterol, Formoterol, Metaproterenol, Pirbuterol, Salbutamol (Albuterol), Salmeterol, Terbutaline among others
• beta-2receptor agonists causes increased heart rate in sinoatrial node (SA node) in addition to increases contractility and automaticity of ventricular cardiac muscle.
The beta-2 adrenergic agonists act mainly on the smooth muscle of the vasculature, bronchial tree, intestines and uterus
In the Git, Beta agonist cause relaxation of smooth muscle and contraction of sphincters leading to constipation (reduced bowel movements)
Retention of urine is as a result of relaxation of detrusor muscle in the bladder
In high doses these agents also act . . .
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