Toxicology
• Copper sulphate is a powerful oxidizing agent and a corrosive acid to mucous membranes (Saravu et al 2007).
• The soluble copper salts such as CuSO4 show limited absorption accounting for their low systemic toxicity. organic copper compounds induce more severe systemic effects.
• The lethal dose is about about 10-20 g in an adult (Akintonwa et al, 1989 cited by IPCS INCHEM; Saravu et al 2007).
The mechanism of poisoning is unknown but thought to be related toxicity to some enzyme systems such G6PD and glutathione reductase which can destroy erythrocyte membrane. NADPH is also affected (Roberts and Reigart . . .
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