Fluazuron

  • Fluazuron is an insect growth regulator belonging to the class of benzoylphenyl urea derivatives, a class of chitin synthesis inhibitors.

  • The substance is intended for tick control in beef cattle, applied topically as a pour-on.
  • Oral administration of (radiolabelled) fluazuron to rats led to high oral absorption (60 % within 24 hours after administration); elimination was primarily via faeces (59% within
    1 week after administration, compared to 3% via urine).
  • Most of the absorbed dose was retained in the adipose tissues as unchanged fluazuron. The fraction in fat tissues was released slowly . . .

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