PGE2 (e.g Dinoprostone) and PGF2alfa (e.g. Carboprost) are theoretically superior to oxytocin for inducing labour in women with eclampsia, preeclampsia and other cardiovascular diseases because, unlike oxytocin that is intrinsically antidiuretic, prostaglandins act renally to enhance salt and water loss (natriuresis).
Additionally, studies have shown that PGE2 increases the chances of achieving vaginal birth with lower probability of interventions in labour such as epidural analgesia and fetal heart rate monitoring.
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