Ringers Lactate solution (RL) is a balanced, alkalinizing, and hypotonic crystalloid solution containing physiologic concentrations of Na+, K+, Ca2+, Cl−, and lactate.
Lactate ions are predominantly metabolized in the liver either back to glucose (gluconeogenesis), or to CO2 and H2O. Both processes require sufficient amounts of O2 to be supplied to the liver. For every lactate that is metabolized, one H+ ion is used for every one HCO3 ion generated (hence the alkalinizing effect under aerobic conditions).
Indications
Lactated Ringer's Injection has value as a source of water and electrolytes.
Many studies, and in particular, animal experiments, have shown . . .
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